Senior Scientist, Antibody and Protein Engineering

Company: Regeneron Pharmaceuticals, Inc.
Location: Tarrytown
Posted on: January 27, 2026

Job Description:

We are seeking a highly motivated and results-driven Senior Scientist to join our fast-paced and innovative Bispecifics & Antibody Engineering Department. You will be part of a group of diverse talents responsible for the design, production and characterization of next-generation antibody and protein therapeutics for infectious disease targets at Regeneron. This position will have a direct impact in innovative platform development at this exciting time, as significant advancements in antibody engineering has already propelled approvals of multiple next-gen antibody-based therapies in many indications. As a Senior Scientist, a typical day may include the following: Apply molecular and structural biology expertise to design innovative bi- and multi-specific antibodies with improved potency, selectivity and developability. Produce novel alternative format antibodies through mammalian expression and purification. Perform and troubleshoot in vitro bioanalytical and cell-based assays (SDS-PAGE, western blotting, flow cytometry binding, ELISA, qPCR). Collaborate with stakeholders in Infectious Disease to align on engineered antibody designs, research objectives, and next steps. Effectively communicate results to management and stakeholders in group and departmental meetings and maintain timely records in electronic lab notebooks. This role may be for you if: You are results-driven, can learn new skills quickly, and demonstrate a strong track record of troubleshooting assays. You have a background in infectious disease and antibody engineering. You are experienced in molecular biology and protein production. You have strong organizational, communication, and presentation skills. You enjoy working collaboratively in teams with diverse backgrounds and can handle multiple projects simultaneously. To be considered for this role you must have a PhD in molecular biology, cell biology, biochemistry, or a related field, with at least 1 year of relevant experience in academia or industry. Desired candidates must have hands-on experience with cloning, antibody expression in mammalian cell lines, antibody purification (i.e., experience with AKTA) and biochemical/biophysical characterization. Familiarity with flow cytometry, neutralization assays, and/or structural biology is preferred but not required. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regenerons roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regenerons on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $109,900.00 - $179,300.00

Keywords: Regeneron Pharmaceuticals, Inc., New Britain , Senior Scientist, Antibody and Protein Engineering, Science, Research & Development , Tarrytown, Connecticut